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Third, mechanistic studies, both clinical and translational, which probe inflammatory signaling, insulin/IGF pathways, and the gut microenvironment to determine whether observed benefits are predominantly tumorintrinsic, hostsystemic, or both, said Cuomo

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To our knowledge, this is the first study to examine weight loss in patients with overweight or obesity who are living with diabetes and prescribed GLP-1 agonists in the real world

Prakoso D, De Blasio MJ, Tate M, Kiriazis H, Donner DG, Qian H, Nash D, Deo M, Weeks KL, Parry LJ, Gregorevic P, McMullen JR, Ritchie RH (2020) Gene therapy targeting cardiac phosphoinositide 3-kinase (p110alpha) attenuates cardiac remodeling in type 2 diabetes