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Another meta-analysis by Bagheri-Hosseinabadi et al

Key findings from SURMOUNT-1 include a mean weight loss of 15.0% at the 5mg dose, 19.5% at the 10mg dose, and 20.9% at the 15mg dose over 72 weeks

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While these mechanistic insights support the biological plausibility of IFs benefits, most data come from animal studies or short-term human trials, raising questions about their generalizability to long-term clinical outcomes