These findings highlight the need for prospective studies that integrate longitudinal assessments of weight, thyroid function, and levothyroxine dosing to validate these results and clarify the mechanisms linking GLP-1RA use to cardiovascular outcomes, including atrial fibrillation/flutter and stroke
The ADA recommends HbA1c monitoring every 3 months until targets are achieved, then every 6 months
(Reference Gayatri, Kumar and Kumar28) , participants were not randomly assigned to the intervention and control groups, and seven studies described an allocation concealment method (Reference Hassan, Alalfy and Hassan18,Reference Badawy, El Nashar and El Totongy20Reference Hashim, Anwar and El-Fatah22,Reference Elgindy, El-Huseiny and Mostafa23,Reference Ghomian, Khadem and Moeindarbari5,Reference Maged, Elsawah and Abdelhafez8)
For growth hormone peptides (sermorelin, ipamorelin), baseline IGF-1 and growth hormone labs are helpful to track progress and ensure safe dosing
