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The efficacy and safety of novel classes of glucose-lowering drugs for cardiovascular outcomes: a network meta-analysis of randomized clinical trials

TRD, treatment resistant depression

TB-500 is a synthetic analogue of thymosin beta-4, a 43-amino acid protein involved in cell migration, differentiation, and tissue repair, while BPC-157 (Body Protection Compound-157) is a pentadecapeptide derived from a protective protein found in human gastric juice

Unfortunately, a randomized trial on diabetes or obesity with cancer as a primary endpoint would be scarcely feasible, and observational studies suffer from the very same issues of underdiagnosis and misdiagnosis