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Genistein, a soy isoflavone that preferentially binds to ER, has been shown to reduce hypoxia-induced hydrogen peroxide (H 2 O 2 ) production, increase Bcl-2 expression, decrease cytochrome c release from mitochondria, and significantly lower apoptosis rates associated with hypoxia (69)

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10.1016/0026-0495(92)90061-E Ishikura H, Matsuo N, Matsubara M, Ishihara T, Takeyama N, Tanaka T: Valproic acid overdose and L-carnitine therapy

For practical investigation, DSIP's subcutaneous route and existing human data provide a starting point, limited as that data may be