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Meanwhile, the process of mitochondrial biogenesis keeps in a dynamic balance, which undergoes through constant fusion and fission

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Safety and efficacy of eculizumab for the prevention of antibody-mediated rejection after deceased-donor kidney transplantation in patients with preformed donor-specific antibodies

A greater understanding of the mechanisms responsible for the clinical and metabolic effects of the poly-agonists, the balance of receptor agonism needed for optimal effects, and the heterogeneity in response among individual patients and different patient populations will be important to guide future drug development and clinical application