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Some people notice mild nausea or reduced appetite within the first few hours of their initial injection, but meaningful therapeutic effects such as sustained appetite reduction and early weight changes typically develop over the first four to eight weeks as the dose is gradually escalated

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Psychiatric Effects In addition to physical complications, some patients have reported psychiatric side effects such as depression, anxiety, and suicidal thoughts after taking GLP-1 weight loss medications

O., Nelson, A., Skafida, M