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First, withdraw the needle immediately and apply gentle pressure to the injection site with clean gauze or a cotton ball for 12 minutes to minimize bleeding and prevent hematoma formation

Gastrointestinal side effects For those who experience side effects, most people will feel them along the digestive tract

However, new FDA policies implemented in 2025 have made all compounded semaglutide and tirzepatide unavailable as of May 22, 2025, requiring patients to transition to FDA-approved branded versions

It remains however to be proven to which extent these described mechanisms are related to the modest blood pressure decrease observed in humans and whether they contribute to stroke prevention