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In this Review, we summarize current preclinical and clinical evidence, showing that the riskbenefit profile of GLP1RAs remains favourable in individuals with T2DM and obesity, although caution is warranted in those with a low cardiometabolic risk, for whom the potential risks of cancer might outweigh any expected benefits

10.1038/nbt.1503 2 Akhavan-TavakoliM.FardM.KhanjaniS.ZareS.EdalatkhahH.MehrabaniD.et al (2017)

Desigualdades sanitarias El organismo advierte que, sin polticas deliberadas, el acceso a GLP-1 podra agravar desigualdades sanitarias

Together with recent findings, these findings suggest that while LPS and semaglutide act on different neuronal populations, they induce overlapping molecular programs that synergize to modulate immune responses