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In addition, gene expression analysis revealed genes related to oxidative stress, ER stress, apoptosis, EMT, cell proliferation, cytoskeleton, and histones

Abdul-Ghani M, Del Prato S, Chilton R, DeFronzo RA

If you are unsure about your injection technique or worry about bumps, ask a clinician to watch you give an injection so they can confirm your technique and the correct needle size