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Most people notice steadier energy, improved digestion, and better balance within the first few weeks

N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter internalization

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If PT-141 nausea is intolerable, reduce the dose to 0.5 mg, administer after a light meal, and consider 10 mg oral domperidone 30 minutes before injection to blunt the emetic reflex