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All experimental protocols were approved by the Institutional Animal Care and Use Committee of the State University of New York at Buffalo and conformed to the National Institutes of Health's Guide for the Care and Use of Laboratory Animals

Patients with visceral obesity demonstrate increased LV myocardial mass, concentric LV hypertrophy and diastolic dysfunction

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The compound of any one of the preceding clauses wherein L comprises a divalent polyglutamic acid radical, where at least one glutamic acid forms an amide with an aminopolyhydroxy radical