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Non-invasive and conservative approaches are often preferred initially or in asymptomatic cases, with treatment tailored to individual patient needs and preferences

The wound is closed in three layers (mucosa, muscle, skin) to restore lip continuity

Calorie restriction in individuals with T2D contributes to weight loss, positively influencing insulin sensitivity and glycaemic control [92]

This suggested that the initial compound had likely degraded through hydrolysis to a sulfonic acid derivative 27 with the separate imidazole leaving group present in the mixture, a hypothesis that was confirmed by LC-MS analysis of the original compound stock (Supplementary Fig