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Key takeaways GLP-1 (glucagon-like peptide-1) is a naturally occurring hormone that helps reduce appetite, regulate blood sugar levels and slow digestion

doi: 10.3389/fnagi.2014.00217, 21 CoetseeC.TerblancheE

Amylin receptors consist of calcitonin receptor (CALCR) heterodimerized with receptor activity-modifying proteins (RAMPs 1, 2, or 3), creating distinct receptor subtypes with tissue-specific distribution

Ultimately, 706 participants met the eligibility criteria and were randomly assigned to one of several treatment arms: once-weekly subcutaneous injections of Cagrilintide at doses of 0.3, 0.6, 1.2, 2.4, or 4.5 mg, once-daily liraglutide 3.0 mg, or a volume-matched placebo