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A June 2004 study found that NRT clinical trials were generally not blind as claimed in that "subjects accurately judged treatment assignment at a rate significantly above chance." If clinical trial participants could tell whether or not their nicotine gum or lozenge was delivering nicotine or was instead an empty placebo, it could explain why NRT efficacy is so high in clinical trials yet falls flat on its face the moment it exits the trial clinic's doors

The safety of e-cigarettes is unclear, but they still contain nicotine, which can affect heart rhythm

Riders get lapped late in the race when the situation is at its worst

HSV-1 quickly loses viability outside the human body, making infection through drink sharing unlikely