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Mitochondria are often referred to as the powerhouses of the cell because they generate the energy needed to support nearly every function in the body

9 Studies with follow-up of more than 1 year At longer follow-up periods, no significant differences were found between the PRP group and non-PRP group on Lysholm score, Ikeuchi grade, and Visual Analog Scale (VAS) for pain at the last follow-up, as reported by numerous studies

Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival

However, it can severely reduce quality of life and may present the risk of serious complications when left untreated