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Without systematic tracking, you may either stop treatment too early (missing additional benefits) or continue too long at a dose that is not working
Animal studies show embryo-fetal toxicity
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A more recent randomized, double-blind, placebo-controlled study in 30 patients with type 2 diabetes found that intravenous infusion of 600 mg of lipoic acid improved the response to the endothelium-dependent vasodilator acetylcholine but not to the endothelium-independent vasodilator, glycerol trinitrate (63)
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