el tirzepatide reduces food intake and appetite, and affects brain functioning, more than placebo and liraglutide Semaglutide vs. tirzepatide: Comparing weight

Phase 2 trial results, published in 2023 in the New England Journal of Medicine (Jastreboff et al., NEJM 2023), demonstrated that participants receiving the highest dose of retatrutide lost an average of approximately 24% of their body weight over 48 weeks a finding that attracted considerable attention from the medical and scientific communities

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The intake also doesnt include pancreatitis, gastroparesis, anorexia or bulimia, an opiate or alcohol screen, an allergy screen of any kind, or a medication list (current meds is a Yes/No only)