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SPR analysis further determined the binding affinity to be 490.7 nM for prothrombin 210.3 nM for collagen and 2.57 M for fibrinogen, respectively (Supplementary Fig

Anal Bioanal Chem 405:41494158

Although fluids dont present the same aspiration risk as semi-solids or solids, there is still delayed gastric emptying for fluids, even though the delay is not as marked as for food, in patients using these drugs