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This approach integrates high-resolution mass spectrometry, selective enrichment, and bioinformatics-driven annotation to reveal how this modification influences protein function, antioxidant defense, and disease-related signaling pathways

These eligibility criteria include a BMI of at least 30 or a BMI of at least 27 with weight-related comorbidities, such as hypertension, type 2 diabetes, OSA, or high cholesterol, and previous participation in a structured weight management program