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The data is striking: in a Phase 2 trial published in the New England Journal of Medicine, the highest doses produced an average ~24% body-weight reduction at 11 months more than any currently approved weight-loss drug (American Diabetes Association)

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While some are FDA-approved for chronic weight management (Wegovy, Saxenda, Zepbound), others are approved only for diabetes (Ozempic, Trulicity, Victoza)