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The present study, as part of the Global Burden of Diseases, Risk Factors, and Injuries Study (GBD) 2020, re-estimated the continuous doseresponse relationships (the mean risk functions and associated uncertainty estimates) between current smoking and 36 health outcomes (Supplementary Table 1) by identifying input studies using a systematic review approach and employing a meta-analytic method 28

Future research should continue to explore the underlying factors influencing these perceptions to develop more effective strategies for reducing e-cigarette use in this population

The lower tar and nicotine numbers found on cigarette packages represent the levels produced when machine "smoked" by a smoking machine test method

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