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In CIPN in vivo models induced by cisplatin, postmitotic sensory neurons in the dorsal root ganglion (DRG) are particularly sensitive to cisplatin injury, and axonal damage induced by cisplatin involves multiple events, including ROS generation, suggesting that antioxidants may help reduce the neurotoxicity of cisplatin [124, 125]

Everything felt fine until the third month when her dose increased to 1.7 mg

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5 January 2018