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A borderline association between a high prothrombin time, as an index of a good prognosis, and GSTT1 homozygous deletion was established, indicating that patients with this polymorphism are more likely to survive after NAC treatment for APAP poisoning

Risk of bias and GRADE assessment Most studies were at low risk of bias or some concerns in the five domains evaluated (Fig

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The measurement of physiological indexes Physiological measurements were carried out for each group of samples