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The subsequent downstream signaling cascade initiated from substrates of the insulin receptor activates kinases and transcription factors vital in promoting cell metabolism, neuronal growth and differentiation, gene transcription, synaptic plasticity, and neuroprotection [133] (Fig

(2014) An introduction to the wound healing assay using live-cell microscopy

10.1093/toxsci/kfy159 4 BhargavaV.SinghK.MeenaP.SanyalR

The researchers found that three cell lines with high GLP-1 receptor expression showed significant growth when exposed to the drug, with increases of 19% and 22% in two cell models