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137 In GC, the novel natural product inhibitor of STAT3 termed XYA-2 might exert its anticancer activity by synergistically inhibiting the expression of MYC and ZIP10, two downstream genes of STAT3 in vitro and in vivo

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Some patients improved to such an extent that they may no longer require CPAP therapy, the researchers found, a potential boon for the many patients who dont use the machines and a development the studys lead author, Atul Malhotra, said could potentially transform how clinicians approach and treat the condition