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SESN2-siRNA or non-silencing siRNA was diluted in transfection medium to a final concentration of 70 nM, mixed with siRNA transfection reagent, incubated for 20 min at room temperature, and added to the cells

Maharjan R, Lim DS, Baik HJ, Park HE, Kim MS, Kim KH, et al

This treatment is primarily used for reducing fat around areas like the chin, jawline, and underarms, though it can be applied to other parts of the body as well