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Outcome measures include neurological severity scoring, rotarod and beam walk performance, histological assessment of lesion volume, and immunohistochemistry for axonal markers and myelin basic protein
As such, a stable GIP agonist has been demonstrated to improve bone quality in rats [867], whereas DPP-4 inhibition positively modified bone composition but not bone microstructure in high fat fed mice [868]
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This fundamental role in cytoskeletal organization positions T4 as a key mediator of cellular motility and wound healing processes
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