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5 Conclusion This MR study demonstrated a causal relationship between Cu levels and an increased risk of GD, indicating that an increase in Cu levels could potentially elevate the risk of GD by 18.3% ( p = 0.025)

GPx4 uses the reducing power of glutathione to convert highly toxic lipid hydroperoxides into harmless, non-toxic lipid alcohols

Figure 4 3.6 Association between GLP-1RA exposure and any substance use disorder Exposure to GLP-1 RA was associated with significantly lower odds of developing any substance use disorder