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The presence of GLP-1R in MCs has been confirmed by multiple research groups, including our own 5,15,16 and ex vivo data have shown that MCs increase their action potential firing frequency after the addition of both GLP-1 and the GLP-1R agonist exendin-4 17

Takes us back in lots of ways to the energy price shock that started in 2021 and went through all of 2022, where we did see, I think, a hit to European manufacturing that had kind of a long tail to it