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After 24 weeks, there was a significant improvement in HbA1c, fasting insulin levels, and triglyceride concentrations, along with a substantial reduction in waist circumference and body weight

Newer molecules were specifically engineered for longer activity, allowing once-weekly dosing

Additionally, these agents mitigate oxidative stress through upregulation of antioxidant pathways, including NRF2 (nuclear factor erythroid 2-related factor 2), enhance mitochondrial function, and reduce pathological -synuclein aggregation [56, 57]

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