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[10] [2] The medication also slows gastric emptying and acts on central appetite centers in the hypothalamus, leading to reduced caloric intake and subsequent weight loss

Glucose monitoring may be especially important for patients using insulin or sulfonylureas

Semaglutide enhances glucose-dependent insulin secretion, suppresses inappropriate glucagon release, delays gastric emptying, and reduces appetite via central nervous system pathways

Several studies have examined what happens when patients switch from GLP-1 receptor agonists like semaglutide to tirzepatide, and the results are encouraging