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To address the low water solubility and bioavailability, a platelet membrane (PM)-coated nanoparticle (NP) system was developed for targeted delivery of BBR (PM@Ber-NP) to inflammatory lungs of an house dust mite (HDM)-induced asthma mouse model [61]

The transcriptional upregulation of Ppara and Ppargc1a observed here reflects glucagon-driven mitochondrial activation [49], while the downregulation of lipogenic genes ( Fasn , Scd2 ) may stem from GIP receptor activation in adipocytes, redirecting nutrient flux away from storage

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