If your vial has been frozen at any point, including during shipping, do not use it
For now, the agency is monitoring the situation
Semaglutide works by shrinking fat cells, but it simultaneously multiplies the number of fat cells you have so it is probable that you will need to use the medication as a life-long therapy to prevent weight gain in the future unless you have a significant lifestyle change

Semaglutide (20 mg) Key Features and Benefits Defined GLP-1 analog structure : Synthetic 31-amino-acid GLP-1 receptor agonist with Lys26 acylation via -glutamic acid and Ado linkers High analytical quality : Typically 98% purity verified by HPLC , with structural confirmation by LC-MS 20 mg research vial : Supports dose-ranging, formulation, and comparative pharmacology studies Consistent physicochemical profile : Molecular weight, sequence, and lipid side-chain architecture align with materials used in nonclinical and clinical research Broad research relevance : Studied in glucose homeostasis , appetite regulation , gastric motility , and body-weight models Stable lyophilized format : Freeze-dried presentation supports controlled storage and transport Research-focused supply : Frequently selected by institutions that order semaglutide peptide for metabolism and pharmacology research For laboratory research use only