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Early human trials in people with obesity found that daily AOD9604 was well tolerated and had a safety profile similar to placebo, with no major effects on glucose metabolism or IGF1, though weightloss results were modest and inconsistent

Injections can raise blood levels quickly and relieve deficiency symptoms, but they are not a validated weight-loss therapy for healthy adults

The best needle for B12 injection into fat tissue would be within the 4-5 mm size range, combined with a gauge of 30G or higher

This effect makes 5 amino 1mq particularly valuable for individuals struggling with prediabetes or insulin resistance