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While all previous studies of amantadine as an antidyskinetic agent tested its symptomatic effect in PD patients who had established LIDs, the PREMANDYSK trial assessed if early adjunct therapy with amantadine has the potential to reduce dyskinesia risk in levodopa-treated early PD patients without LIDs [135]
Diabetes Res Clin Pract (2016) 114:16072.10.1016/j.diabres.2015.12.004 7 NauckMAStewartMWPerkinsCJones-LeoneAYangFPerryCet alEfficacy and safety of once-weekly GLP-1 receptor agonist albiglutide (HARMONY 2): 52 week primary endpoint results from a randomised, placebo-controlled trial in patients with type 2 diabetes mellitus inadequately controlled with diet and exercise
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