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In T2D, therapeutic options, such as dipeptidyl peptidase-4 (DPP-4) inhibitors, incretin-based drugs, and GLP-1 analogues, target -cell function, but not all patients are responsive and approximately 50% ultimately require daily insulin injections due to -cell exhaustion and death (149)

It plays an important role in stimulating GLP-1 and satiety at a brain-body level

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The peptide demonstrates protective effects against gastric ulceration, promotes healing of intestinal lesions, and modulates gut inflammation through multiple pathways