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In people with obesity and established cardiovascular disease but without diabetes, semaglutide 2.4 mg resulted in 20% reduction in major adverse cardiovascular events [(MACE), death from cardiovascular causes, nonfatal myocardial infarction or nonfatal stroke] compared to placebo (SELECT trial) after a mean follow-up of 39.8 months this is the first trial demonstrating cardiovascular benefit for an obesity pharmacotherapy [110]

adults reporting they've used the medicine for weight loss at some point, up from 12% last year, according to a June Gallup study.

Byetta and Bydureon BCise Byetta (exenatide) is approved to improve blood sugar control in adults with type 2 diabetes