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Differences in core materials and surface chemistry lead to distinct corona compositions, which in turn exert integrated effects on endothelial interactions, immune recognition and clearance pathways [41,42,43,44,45]

In fact, PWS subjects die prematurely from complications conventionally related to obesity, including diabetes mellitus, metabolic syndrome, sleep apnea, respiratory insufficiency, and cardiovascular disease

Since 2019, the American Society for Reproductive Medicine has classified ovarian tissue cryopreservation as an established, non-experimental method for fertility preservation (65)

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