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This double-blind, randomized, 26-week superiority trial compared 2 mg of exenatide injection once weekly plus oral placebo (n = 160), 100 mg of oral sitagliptin plus once-weekly injected placebo (n = 166), and 45 mg of oral pioglitazone once-daily plus once-weekly injected placebo (n = 165)

Key Takeaways GLP-1 RAs are a mass-market chronic therapy category where effective exclusivity is determined by layered patent families plus regulatory exclusivities and litigation

This is the most critical part of the technique