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Warning signs include: Sudden rash or hives spreading across the body Generalized itching that is not isolated to the application site Swelling of the face, lips, tongue, or throat Difficulty breathing or shortness of breath Symptoms suggestive of a severe allergic reaction (anaphylaxis) require prompt medical attention

This is particularly important for newer entrants, where published clinical evidence may still be limited

A dosage change may be needed if blood sugar remains high, weight loss has stalled, or side effects are interfering with daily life