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35,36 EMERGING AGENTS IN THE PIPELINE Several late-stage IBTs are expected to expand the weight-management landscape in 2026 or later, including CagriSema, a combination of semaglutide and cagrilintide (a long-acting amylin analogue regulating appetite and glucose)

It is important to note that the BPC-157 used in research is produced by chemical synthesis (solid-phase peptide synthesis), and not extracted directly from gastric juice

For example, MDR1 gene augments ferroptosis sensitivity by promoting GSH efflux, while cysteine dioxygenase 1 (CDO1) increases ferroptosis sensitivity by depleting cysteine and GSH ( Figure 1 )