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This capability is critical for uncovering disease mechanisms and discovering novel biomarkers [278, 279]

Del Orbe BarretoRArrizabalagaBde la HozABAragesPGarcia-RuizJCArrietaAet alSevere neonatal jaundice due to a de novo glucose-6-phosphate dehydrogenase deficient mutation

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Lipid composition also plays a central role in redox homeostasis, which is the cellular system that controls the balance of oxidative and reducing reactions ( The lipid and protein homeostasis systems also control the catabolism of lipids, including through the process of the process of -oxidation of fatty acids in mitochondria and peroxisomes, which generates acetyl-CoA, a key substrate in the tricarboxylic acid (TCA) cycle