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Side effects, mainly nausea and gastrointestinal symptoms, are real and worth discussing with a clinician

As compared to healthy controls, subjects with current or remitted MDD presented similarly lower mean C2 levels (Cohens d = 0.2, p 1e-4)

Depression is frequently associated with chronic low-grade inflammation, and gut microbiota influence the intensity of this inflammatory response by affecting immune cell activity and cytokine secretion

We suspect the large size 64 and complex protein folding with -helical structures at the surface of RuBisCO contribute to the ordering of water molecules and efficient ice nucleation