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A double-blind, placebo-controlled trial involving 40 physically active men found that taking 3 grams of MSM before exhaustive exercise decreased the release of inflammatory cytokines and prevented the over-stress of immune cells, compared to a placebo.(3) May Ease Joint Pain MSM is a popular supplement and is often labeled a staple supplement and a potential support to standard treatment and medications among those suffering from arthritic conditions such as osteoarthritis, caused by wear and tear of the cartilage

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A meta-analysis could not be conducted as the studies were too heterogeneous in numerous regards including therapy doses, regimens and route of administration, means of assessing pain, and variety of neuropathic conditions assessed

KPV (Lys-Pro-Val) is the C-terminal tripeptide of alpha-melanocyte-stimulating hormone (-MSH), with a molecular weight of approximately 340 Da