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Expanding this knowledge will lead to improved genetic risk scores and personalized therapies as new relevant loci are discovered, providing a better picture of the genes and regulatory elements involved in T1D onset and progression

Aging Cell 23, e14138

NAMPT and NRK1/2 are also localized to the nucleus and cytosol 48,83,84 , suggesting that only the final step of salvage is performed in the mitochondria, with a mitochondrial NMN transporter, Slc25a45, recently proposed 85