liraglutide to semaglutide The Discovery and Development of and File:Semaglutide vs. liraglutide v01 SVK.png

The most common ones are usually mild and improve over time: Nausea (especially when starting) Diarrhea or constipation Decreased appetite Fatigue during adjustment period Stomach discomfort Serious But Rare Side Effects More serious side effects are uncommon but require medical attention: Severe allergic reactions Pancreatitis (inflammation of the pancreas) Gallbladder problems Low blood sugar (if combined with diabetes medications) Kidney problems Sleep-Related Considerations Some people report temporary sleep changes when starting GLP-1 medications: Initial insomnia or restlessness (usually improves) Changes in dream patterns Temporary fatigue as body adjusts Mood changes that can affect sleep Most sleep-related side effects resolve within a few weeks as your body adapts to the medication

Clinical trial data demonstrates that Wegovy pill produces significant, sustained weight loss when combined with lifestyle modifications like a reduced-calorie diet and increased physical activity

Effect of semaglutide on liver enzymes and lipids: post hoc analysis of STEP trials

Engel with nonarteritic anterior ischemic optic neuropathy, or NAION