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Peptides 12(4):861863 Westgate CSJ et al (2021) Understanding the link between obesity and headache- with focus on migraine and idiopathic intracranial hypertension

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In addition, STZ-induced C57BL/6 mice and Park2 knockout (KO) mice were used as models, and hypoxia-inducible factor 1 subunit (HIF-1) was found to up-regulate mitophagy in DPN mice, thus exerting some therapeutic effects on DPN [169]