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Clinical trials demonstrated average weight loss of 6 to 8% of body weight over 56 weeks, with meaningful improvements in cardiometabolic risk factors

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Ronis MJJ, Huang J, Crouch J, Mercado C, Irby D, Valentine CR, Lumpkin CL, Ingelman-sundberg M, Badger TM: Cytochrome P450 CYP 2E1 induction during chronic alcohol exposure occurs by a two-step mechanism associated with blood alcohol concentration in rats

The mean accumulated costs produced by type 2 diabetes per patient at 10 and 20 years is 2,302.51 USD and 4,398.7 USD, respectively.4 There are currently 12 medication groups approved for the management of diabetes and some of them have been associated with significant gastrointestinal adverse effects